Short-acting type H1 antihistamines these medications, including diphenhydramine (Benadryl), are the primary treatment of mild cases of hives and angioedema.
Acquired angioedema is a hypersensitivity disorder that presents as edema of the subcutaneous tissues and mucosa, typically involving the upper airways or gastrointestinal tract, and often accompanied by urticaria.
Angioedema, which is also called by others as Quincke’s edema, is the swelling occurring in the tissue under the skin’s surface. The skin ailment is usually an allergic reaction to a medication or food.
Hives is an allergic skin reaction that comes on suddenly. The hives themselves are slightly raised, smooth, flat-topped bumps called wheals (look like mosquito bites) and welts that are usually more red in color than the surrounding skin and cause severe itching.
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